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Symbol
Name
ID

Hmga2
high mobility group AT-hook 2
MGI:101761

Phenotype annotations related to reproductive system

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Hypospadias	Testicular seminoma	Dysgerminoma	Ovarian papillary adenocarcinoma
Disease(s) Associated with HMGA2	Hypospadias	Testicular seminoma	Dysgerminoma	Ovarian papillary adenocarcinoma
ovarian cancer
Silver-Russell syndrome

Mouse Phenotypes

reproductive system phenotype

abnormal sperm flagellum morphology

azoospermia

oligozoospermia

teratozoospermia

abnormal sperm head morphology

abnormal spermatogonia morphology

increased male germ cell apoptosis

short perineum

decreased seminal vesicle weight

small ovary

decreased testis weight

small testis

cryptorchism

penis prolapse

small uterus

decreased epididymis weight

priapism

abnormal estrous cycle

female infertility

infertility

male infertility

Availability

Mouse Genotype

Hmga2^em1Sson/Hmga2^em1Sson

Hmga2^pg/Hmga2^pg

!

Hmga2^tm1Cha/Hmga2^tm1Cha

Hmga2^em1Sson/Hmga2⁺

*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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